Thank goodness, I left my MacBook Pro on El Capitan and when I need to use my Mac mini, I use screen sharing and run the Sierra computer from the MacBook Pro. The only problem is that USB Overdrive isn't updated all that often. While Steermouse has better mouse acceleration than Apple's drivers, USB Overdrive seems to do it right even better. This is an ergonomic nightmare for someone using the computer professionally. I find that you can get much better feel to the mouse when adjusting the acceleration settings than with Steermouse. I find myself constantly having to "work" the view into position. The practical side of this is that many software applications are difficult to use with a mouse. Scrolling is reactive and consistent on El Capitan. One increment movement of the mouse wheel and scrolling takes place. On OS X El Capitan on another computer, using the same mouse, the scroll behavior is correct. Almost as if there is some latency involved. It’s nice because I know a lot of people complain. You can pop this thing out to clean anything in there that might need cleaning you’ve got a back and a forward button of course you’ve got your scroll and your click. The degree to which one must move the scroll wheel for movement to initiate does not seem to be consistent. It’s a Logitech M570 it’s got a nice little blue ball, and it glides really smooth. In fact, In order to initiate scrolling, one must scroll the wheel several increments for movement to kick in.
When scrolling with a generic USB mouse (no 3rd party driver) that has an incremental scroll wheel, the screen or view does not scroll with each increment of movement of the wheel. The problem I am seeing is also very straight forward. Installed the release version of MacOS Sierra 10.12.1 on my Mac mini (Late 2012) and the problems with scrolling described here and in other discussions continue.